Lori, I am taking Pramipexole Dihydro in the evening to help during the night and that seems to be working fairly well. I have also switched chairs that I sit in at my desk. I have a lounge chair and this desk chair that form sort of a basket shape and I wonder if that puts pressure on my hips effecting the feelings in my legs. This straight back kitchen chair seems to provide some improvement. Another thing I have undertaken is to give up caffeine. I've switched to apple or cranberry juice and I think I see somewhat of an improvement in the condition of my legs. Little quick to draw conclusions, but I keep experimenting. I'm also doing some back stretches in the morning which I hope will help. This achy, jumpy leg thing probably needs multiple approaches. No magic bullet.