buprenorphine is a Godsend

Hi Bearpaws, it sounds like you and I have a lot in common, what with the augmentation, etc etc. I'm a bit surprised you were prescribed Suboxone instead of just buprenorphine, since the naloxone component of Suboxone is intended to keep former narcotic addicts from injecting it IV, and doubt if that applies to you 😉
I had to increased the strength of the buprenorphine wafers a bit recently, so now I take 3/4 of a wafer under my tongue every night, and it's working well. No restless legs day or night. Each wafer has 0.4 mg of buprenorphine.
I also asked my neurologist if she could prescribe Belbuca instead of the compounded buprenorphine. Belbuca is buprenorphine in a patch form that is absorbed through the inside of the cheek. I'll be starting at a low dose: 75-150 mcg/day. It's expensive though; $200 a month with insurance.
I agree with the recommendation of Miralax for constipation. You might also try cutting down the dose. The half-life of buprenorphine is very long; about 24 hours.

Hello RLSman - I was just prescribed Buprenorphine-Naloxol ("Suboxone"} myself, just under 2 weeks ago, after having taken Requip for almost 17 years! After this very short trial of Suboxone, it seems to be stifling my leg and arm RLS symptoms so far! Previously, I developed the classic "augmentation" while taking the Dopamine Agonist (Requip), requiring a bigger and bigger dose as the years went by, and seeing the spread of RLS symptoms to my left shoulder, and most-recently to my right shoulder. And along these past several years, my neurologist tried all the other meds like the transdermal patch, gabapentin, pre-gabalin, Hydrocodone, and extended release Ropinerole ("Requip"😉. But the other meds didn't knock out the RLS in my leg and allow me to get some sleep like the Ropinerole did. So I went back to Ropinerole, but I've paid the big price of augmentation as I just mentioned. Within the past year I've been very fortunate to have access to a "quality sleep care center" (as the Restless Leg Syndrome Foundation/Organization calls them) in the Bay Area of California. The doctor there had me try gabapentin again, along with some of my Ropinerole, in an effort to reduce my use of Ropinerole, but it just didn't work for me (interesting to note that neurontin (gabapentin) was the first medication that was ever prescribed to me in my very early years of treating RLS, and it worked way back then! But when I later transitioned to regular release Requip for many years, re-use of the neurontin or gabapentin stopped working like it had, early on). I've only been using the Suboxone for about 2 weeks now, taking one-half a strip in the late morning and the other half a couple hours before bedtime. I'm anxious about how long and how well this new treatment will be effective. And the side-effects of Suboxone have hit me, too (Opioid-Induced Constipation), and my anxiety has gotten pretty bad and worrisome. It's a difficult road to travel, changing meds "cold turkey" and trying to deal with a whole new set of side-effects. I would appreciate hearing back from you as proceed with your own trial of Buprenorphine. Many thanks.

How awesome that you found something that brings you relief, . That was smart to find a pharmacist who could customize the medication for you. I hope you are able to get off your other medications and that you remain symptom-free. Thanks for sharing what helps. Warm wishes. - Lori (Team Member)