After 40 plus years of RLS and a variety of medications, over the last 8 years or so I had been using Pramipexol successfully for 24 hours of relief. The relief time began to wane periodically and my doctor allowed an increase to 3 tablets at night. The result worked for another couple years but then continued to decline to inconsistent times and hours, which is where I am now. I am trying to concentrate and document times and potential triggers. One thing I ran across was the mention of RLS and kidney disease which I am beginning to research. In the meantime, I have noticed that when I play the piano during these episodes, during that 45 minutes to an hour playing the piano I usually experience zero symptoms. Sometimes it allows me to sleep through the night, sometimes it lasts awhile, but resumes as soon as I get in bed. It seems like the difference is how tired I am. Bear in mind that I continue to take 2 pramipexole tablets and an additional one only when absolutely necessary that I get some sleep. My question is, does anyone on the forum find that a creative activity has given some measure of relief? I often play word games on a tablet that will work but not as thoroughly.